[Molecular genetics in nephrology. Genetic kidney diseases provide clues for understanding the pathogenesis of proteinuria]
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Updated: Aug 31, 2026

Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
Published on: June 23, 2015
1Medizinische Klinik IV, Nephrologie, Universitätsklinik Freiburg, Freiburg, Deutschland.
Abstract:
Recent progress in defining the genetic basis of inherited glomerular diseases has provided a completely new understanding of the glomerular filter of the kidney and has helped illuminate the pathogenesis of acquired and inherited renal proteinuric diseases. Based on the findings of molecular genetics in nephrology we will discuss the current understanding of the glomerular filter and provide an idea how genetic testing in the future may help to guide therapy in patients suffering from nephrotic syndrome and progressive renal failure.
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