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Our experience with eclampsia in Singapore.

C Y Chen1, K Kwek, K H Tan

  • 1Department of Maternal-Foetal Medicine, KK Women's & Children's Hospital, 100 Bukit Timah Road, Singapore 229899. DrChenCY@hotmail.com

Singapore Medical Journal
|September 25, 2003
PubMed
Summary

Eclampsia remains a significant cause of maternal and fetal complications in Singapore. Indian women and those outside the typical reproductive age are at higher risk, highlighting the importance of antenatal care.

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Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Public Health

Background:

  • Eclampsia is a severe complication of pregnancy characterized by seizures.
  • Understanding its incidence and risk factors is crucial for improving maternal and fetal outcomes.

Purpose of the Study:

  • To determine the incidence and epidemiological factors of eclampsia.
  • To identify preceding symptoms, management, and obstetric outcomes.
  • To assess the impact of eclampsia in a Singaporean tertiary care hospital.

Main Methods:

  • Retrospective study design.
  • Inclusion of all obstetric patients with eclamptic seizures between January 1994 and December 1999.
  • Data collection on demographics, symptoms, management, and outcomes.

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Main Results:

  • Eclampsia incidence was 6.7 per 10,000 deliveries.
  • Indian ethnicity and extremes of reproductive age (younger than 25 or older than 34) were associated with higher incidence.
  • Headache was the most common preceding symptom (64.5%).
  • Maternal mortality rate was 1.6%, with significant morbidity in 24.2% of cases.
  • Perinatal mortality rate was 95.2 per 1,000 births.

Conclusions:

  • Eclampsia continues to be a major contributor to maternal and fetal mortality and morbidity in Singapore.
  • Race and age are identified as significant risk factors.
  • Antenatal care plays a vital role in mitigating perinatal mortality and maternal complications.