Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Endometriosis and malignoma].

U Ulrich1, O Richter, E Wardelmann

  • 1Zentrum für Geburtshilfe und Frauenheilkunde, and Klinik und Poliklinik für Frauenheilkunde und Geburtschilfe, Klinikum der Universität zu Köln, Cologne. UweAUlrich@AOL.com

Zentralblatt Fur Gynakologie
|September 25, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prediction of Mutations and Outcome in Gastrointestinal Stromal Tumors with Deep Learning: A Multicenter, Multinational Study.

medRxiv : the preprint server for health sciences·2026
Same author

Visual-Numeric Endometriosis Scoring System (VNESS) for mapping surgical findings: A validation study.

Facts, views & vision in ObGyn·2024
Same author

Superficial fibromas with CTNNB1 mutation.

Genes, chromosomes & cancer·2024
Same author

Phenotype analysis of families with TP53 germline variants at the Center for Familial Breast and Ovarian Cancer, Cologne.

Cancer medicine·2024
Same author

Accuracy of ultrasound signs on two-dimensional transvaginal ultrasound in prediction of adenomyosis: prospective multicenter study.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2023
Same author

Humans at the dawn of the in-body electrical nerve stimulation era.

Facts, views & vision in ObGyn·2023
Same journal

About 150 births naturally after previous Caesarean section.

Zentralblatt fur Gynakologie·2010
Same journal

About lutein cysts found in hydrops foetus et placentae.

Zentralblatt fur Gynakologie·2010
Same journal

The potencies of the burner epithelium, especially a tendency to form serous epitrel, squamous and mucosal epithelium.

Zentralblatt fur Gynakologie·2010
Same journal

Two double birth defects causing obstetric difficulties.

Zentralblatt fur Gynakologie·2010
Same journal

The uterine size and fundus level in the first part of pregnancy.

Zentralblatt fur Gynakologie·2010
Same journal

The crossbar interposition.

Zentralblatt fur Gynakologie·2010
See all related articles

Malignant tumors from endometriosis are rare, often affecting the ovary or extragonadal sites like the rectosigmoid. Treatment involves resection, radiotherapy, and potentially progestin therapy for extragonadal cases.

Area of Science:

  • Gynecologic Oncology
  • Oncogenesis
  • Cancer Epidemiology

Context:

  • Malignant tumors originating from endometriosis are uncommon, with approximately 1% frequency.
  • Ovarian involvement accounts for 80% of cases, while 20% affect extragonadal sites.
  • Common extragonadal sites include the rectosigmoid and rectovaginal septum.

Purpose:

  • To review the characteristics, treatment, and risk factors associated with endometriosis-related malignancies.
  • To highlight differences in presentation and treatment response between ovarian and extragonadal endometriosis-associated cancers.
  • To discuss the role of PTEN gene mutations and estrogen replacement therapy in tumorigenesis.

Summary:

  • Complete resection followed by radiotherapy and possibly progestin therapy is the standard treatment for extragonadal endometriosis-associated malignancies.

Related Experiment Videos

  • Endometriosis-associated ovarian carcinomas often present at lower stages and grades but may show reduced chemotherapy response.
  • Unopposed estrogen replacement therapy is contraindicated in women with a history of endometriosis due to increased cancer risk.

    • Impact:

    • Informs clinical management strategies for rare endometriosis-associated cancers.
    • Suggests PTEN gene alterations as potential early markers for malignant transformation.
    • Identifies a link between endometriosis and an elevated risk of non-Hodgkin lymphoma.