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Age-related variations of enzymatic defenses against free radicals and peroxides
Y Artur1, B Herbeth, L Guémouri
1Centre de Médecine Préventive, Vandoeuvre-lès-Nancy, France.
EXS
|January 1, 1992
Abstract:
Superoxide dismutase, glutathione peroxidase and catalase are the three main enzymatic systems of defense of the organism against free radicals and peroxides. A survey of the literature shows that no general tendency of evolution of these systems in aging emerges, even if some recent studies in humans demonstrate the existence of a concomitant decrease in most of the antioxidant enzymes in blood of the elderly. The study of the antioxidant systems and their interrelations in the elderly represents a large field of future investigations.