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Published on: June 23, 2015
[Urinary tract infection: a search for evidence]
Vera H Koch1, Sandra M C Zuccolotto
1Instituto da Criança, Hospital das Clínicas, Universidade de São Paulo (USP), São Paulo, SP, Brazil. vkoch@terra.com.br
Insights
Diagnosis and treatment guidelines for pediatric urinary tract infections (UTIs) are largely opinion-based. More rigorous, double-blind trials are needed to improve the quality of care for children with UTIs.
Area of Science:
- Pediatric Nephrology
- Infectious Diseases
Context:
- Urinary tract infections (UTIs) are common in children.
- Current diagnostic and treatment protocols rely heavily on expert consensus.
- Evidence-based guidelines are crucial for optimal management.
Purpose:
- To review the evidence for diagnosing and treating urinary tract infections in children.
- To identify gaps in current knowledge and practice.
Summary:
- A systematic literature search of Medline and Cochrane databases (1996-2002) identified relevant studies on pediatric UTIs.
- Studies were selected based on methodology, relevance, and clinical applicability, including American Academy of Pediatrics guidelines.
- Findings indicate that consensus statements dominate the field, highlighting a need for higher-quality evidence.
Impact:
- Highlights the need for high-quality, randomized, multicenter, double-blind controlled trials.
- Emphasizes the necessity of evidence-based medicine for improving pediatric UTI diagnosis and management.
- Aims to guide future research and clinical practice in pediatric urology and infectious diseases.
Objective:
To review urinary tract infection in children taking into consideration evidence-based medicine.
Sources:
search of Medline and Cochrane databases, comprising the period between 1996 and 2002, with the following key words: urinary infection, vesicoureteral reflux, children, adolescents, diagnosis and treatment. Cohort studies, quality assurance studies, consensus, meta-analysis studies, randomized controlled trials and audits were selected.
Summary Of The Findings:
The studies were selected according to their methodology, relevance and clinical applicability. Some studies were selected based on the parameters proposed by the American Academy of Pediatrics in 1999 for the diagnosis and treatment of urinary tract infection in children between two months and two years of age.
Conclusions:
Consensus statements on diagnosis and treatment of urinary infection in children and adolescents are still mostly opinion-based. Randomized multicentric controlled trials, with double-blind allocation are necessary to improve quality of diagnosis and management of pediatric urinary tract infection.
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