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Enhanced luminescent assays for hepatitis markers: assessment of post vaccine responses
1Regional Virus Laboratory, Birmingham, West Midlands, England, U.K.
Abstract:
A range of solid phase immunoassays have been developed using enhanced chemiluminescence to provide a signal which can be measured in a qualitative or quantitative manner. The "Amerlite" anti-HBs assay has been used routinely to test more than 3000 post-vaccine anti-HBs levels. The results show that 5% of vaccinees are non-responders, but that more than 30% produce antibody levels greater than 1000 mIU/ml.
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