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Related Experiment Videos

Micronutrient supplementation: when is best and why?

Mary R L'Abbé1, Kevin A Cockell, Nora S Lee

  • 1Bureau of Nutritional Sciences, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, ON K1A 0L2, Canada. mary_l'abbe@hc-sc.gc.ca

The Proceedings of the Nutrition Society
|September 26, 2003
PubMed
Summary
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Nutrient risk assessments establish tolerable upper intake levels (UL) to guide safe food fortification and supplementation strategies. This framework minimizes risks from overconsumption while maximizing public health benefits.

Area of Science:

  • Nutritional Science
  • Public Health Nutrition
  • Risk Assessment

Background:

  • Systematic determination of high nutrient intake effects over time is lacking.
  • Governments and scientific bodies are developing nutrient risk assessment methodologies.
  • Tolerable Upper Intake Levels (UL) are being established to evaluate nutrient safety.

Purpose of the Study:

  • To present a framework for using UL and food consumption data.
  • To assess the appropriateness of food fortification versus supplementation strategies.
  • To evaluate the impact of these strategies on population nutrient intakes.

Main Methods:

  • Establishing the need by assessing the intake gap.
  • Assessing safety by considering the margin of safety and adverse effects.

Related Experiment Videos

  • Estimating exposure using statistical modeling of population intakes.
  • Monitoring intervention impact to ensure benefits and minimize excessive intake.

    • Main Results:

    • The paper provides examples of applying the UL framework.
    • Demonstrates how to compare fortification and supplementation strategies.
    • Illustrates the assessment of population-level nutrient intake impacts.

    Conclusions:

    • A systematic approach using UL optimizes public health benefits of nutrient interventions.
    • This method minimizes risks associated with excessive nutrient intake.
    • It ensures desired benefits are achieved while preventing overconsumption.