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Updated: Aug 31, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Probiotics for the treatment of postoperative complications following intestinal surgery
Paolo Gionchetti1, Cristina Amadini, Fernando Rizzello
1Department of Internal Medicine and Gastroenterology, University of Bologna, Policlinico S. Orsola, Via Massarenti no 9, 40138 Bologna, Italy. paolo@med.unibo.it
Abstract:
Probiotics are living micro-organisms that belong to the normal enteric flora and exert a beneficial effect on health and well-being. The rationale for the therapeutic use of probiotics in pouchitis (the most frequent long-term complication following pouch surgery for ulcerative colitis) and postoperative recurrence in Crohn's disease is based on convincing evidence suggesting a crucial role for the endogenous intestinal microflora in the pathogenesis of these conditions. Positive results have been obtained with the administration of highly concentrated probiotic preparations in preventing the onset and relapses of pouchitis. Further controlled studies are needed to establish the efficacy of probiotics in the prophylaxis of postoperative recurrences of Crohn's disease and in the treatment of mild pouchitis.
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