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Cancer of the nasopharynx: functional surgical salvage
1Department of Surgery, Room 206, Professorial Block, University of Hong Kong Medical Centre, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China. hrmswwi@hkucc.hku.hk
Abstract:
The primary treatment modality for nasopharyngeal carcinoma is radiotherapy (RT). When tumor persists or recurs at the nasopharynx or in the neck after irradiation, then further courses of radiotherapy are associated with recognized morbidities. The swallowing, speech abilities as well as the cervical musculoskeletal functions of the patient may be significantly affected. Surgical salvage of neck disease with radical neck dissection contributes to better tumor control with acceptable morbidity. For localized tumor in the nasopharynx, adequate extirpation of the disease togetherwith the removal of paranasopharyngeal tissue is possible with the anterolateral approach. The operation is not difficult and the associated morbidity is minimal. After a median follow up of 3 years, the 82 patients who underwent this operation demonstrate that with adequate exposure and surgical salvage, satisfactory tumor control rate with good functional outcome is possible.
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Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...