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Updated: Aug 31, 2026

A Microplate Assay to Assess Chemical Effects on RBL-2H3 Mast Cell Degranulation: Effects of Triclosan without Use of an Organic Solvent
Published on: November 1, 2013
Environmental fate of Triclosan in the River Aire Basin, UK
Darius Sabaliunas1, Simon F Webb, Armin Hauk
1Procter & Gamble Technical Centers Ltd., Rusham Park, Whitehall Lane, Egham, Surrey, TW20 9NW, UK. sabaliunas.d@pg.com
Abstract:
The concentrations and removal rate of Triclosan, an antibacterial ingredient in consumer products, were measured at advanced trickling filter (TF) and activated sludge (AS) wastewater treatment plants (WWTPs) in the River Aire basin in the UK in September 2000. Additionally, the in-stream removal of Triclosan was measured directly in Mag Brook, the stream receiving the treated effluent from the TF plant, using a fluorescent dye tracer to determine the water plug travel times. The in-stream removal of the dissolved and un-ionized (i.e. bioavailable) fraction of the compound was measured using semipermeable membrane devices (SPMDs) deployed at various distances downstream from the WWTP discharge point. The estimated removal rates were used in the GREAT-ER (Geography-Referenced Regional Exposure Assessment Tool for European Rivers) model to predict the site-specific distribution of Triclosan concentrations in the Aire basin as well as to calculate regional concentrations. High WWTP (approximately 95%) and in-stream (0.21-0.33 h-1) removal rates of Triclosan in Mag Brook confirm that this chemical is rapidly eliminated from the aquatic environment.
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