Related Experiment Video
Updated: Jan 25, 2026

Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer
Published on: May 10, 2024
Nucleotide sequences of pigeon feather keratin genes
Rieko Takahashi1, Kiso Akahane, Kunio Arai
1Department of Chemistry, Faculty of Science, Josai University, Keyakidai 1-1, Sakado, Saitama 350-0295, Japan. takarie@josai.ac.jp
Abstract:
We analyzed two pigeon feather keratin clones from a cosmid pigeon genomic library. Each of the clones contained three feather keratin genes that had the same general structure: a 5' non-coding region separated by an intron, a protein-coding region encoding a protein of 100 amino acids, and a 3' non-coding region. Length and transcriptional organization of the genes were variable. The length variation, about 1.2-3.7 kb, was mainly due to the difference in the length of the 3' non-coding region, and the longer genes had opposite transcriptional organization in contrast to the shorter genes. The nucleotide sequences of the coding region were very similar among the six genes but not the same.
Related Concept Videos
Nucleotide Excision Repair
Nucleotide Excision Repair
Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
What is Gene Expression?
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...
Proteins: From Genes to Degradation
Transcription is the synthesis of RNA...
Cis-regulatory Sequences
Nucleic Acids and Nucleotides
Deoxyribonucleic Acid (DNA)
DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and the organelles such as chloroplasts and mitochondria....

