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Divinatorins A-C, new neoclerodane diterpenoids from the controlled sage Salvia divinorum
Andrea K Bigham1, Thomas A Munro, Mark A Rizzacasa
1Department of Microbiology and Immunology, School of Chemistry, The University of Melbourne, Victoria, 3010, Australia.
Abstract:
Three new neoclerodane diterpenoids, divinatorins A-C (7-9), have been isolated from the leaves of Salvia divinorum. The compounds were identified by spectroscopic methods as derivatives of the antibiotic (-)-hardwickiic acid (10), which was also isolated, along with four other known terpenoids. Neither the crude extract nor 7-9 displayed antimicrobial activity.
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