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Published on: July 11, 2013
[Prescriptions for individually prepared dermatologic agents. I]
A Fekárová1, Z Gruntová, M Hornácková
1Katedra organizácie a riadenia farmácie, Fakulná lekáren Farmaceutickej fakulty Univerzity Komenského, Bratislava.
This study analyzed dermatological prescriptions in Slovakia, finding solutions are most common, often hydrophilic. Suspensions utilized specific liquid bases or plant oils, with emulsions being least frequent.
Area of Science:
- Dermatology
- Pharmaceutical Sciences
- Medicinal Chemistry
Context:
- Analysis of contemporary medical prescriptions for topical dermatological formulations.
- Comparison with historical district prescription data from Slovakia (1987-1989).
- Focus on solutions, suspensions, and emulsions in extemporaneous preparations.
Purpose:
- To survey and analyze current prescription trends for dermatological solutions, suspensions, and emulsions.
- To compare contemporary prescription patterns with data from 1987 and 1989 in Slovakia.
- To identify prevalent drug classes and formulation bases used in topical dermatological treatments.
Summary:
- A survey of 27 Slovak districts revealed 112 drugs used in dermatological solutions, predominantly hydrophilic and composite.
- Hydrophilic suspensions favored water-glycerol or spirit-water bases, while hydrophobic suspensions primarily used plant oils.
- Emulsions constituted a minor proportion (0.7%) of topical extemporaneous dermatological preparations studied.
Impact:
- Provides insights into historical and contemporary prescription practices in dermatological formulations.
- Highlights the prevalence of specific formulation types and excipients in topical treatments.
- Informs pharmaceutical formulation development and clinical prescribing guidelines for dermatological conditions.
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