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Soap-HT-BLAST: high throughput BLAST based on Web services.

Jiren Wang1, Qing Mu

  • 1BioInformatics Institute, 30 Medical Drive, Singapore 117609. jiren@bii.a-star.edu.sg

Bioinformatics (Oxford, England)
|September 27, 2003
PubMed
Summary
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A new high throughput Basic Local Alignment Search Tool (BLAST) system using web services is now available. This system enables users to run multiple BLAST queries simultaneously in a distributed, parallel internet environment.

Area of Science:

  • Bioinformatics
  • Computational Biology

Background:

  • Web services offer a flexible platform for distributed computing.
  • The Basic Local Alignment Search Tool (BLAST) is a fundamental algorithm in bioinformatics.

Purpose of the Study:

  • To implement a high throughput BLAST system utilizing web services.
  • To provide an alternative and enhanced BLAST querying service.

Main Methods:

  • Development of a web service-based system for BLAST analysis.
  • Implementation of a distributed and parallel processing environment for queries.

Main Results:

  • A functional high throughput BLAST system has been successfully implemented.
  • The system supports the execution of multiple BLAST queries concurrently.

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Conclusions:

  • The developed system offers a viable alternative for high throughput BLAST analysis.
  • It facilitates efficient, parallelized sequence similarity searches over the internet.