Related Experiment Video
Updated: Aug 30, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
[Hemorrhagic gastritis due to cow's milk allergy: report of two cases]
Rodrigo Strehl Machado1, Elisabete Kawakami, Soraya Goshima
1Universidade Federal de São Paulo, São Paulo, SP, Brazil. rodrigo@gastroped.epm.br
Objective:
To report two cases of infants with hemorrhagic gastritis due to cow's milk allergy.
Description:
The clinical features included hematemesis, vomiting and malnutrition. All patients had eosinophilic infiltrate in gastric biopsies and got favorable clinical outcome after cow's milk free diet.
Comments:
Hemorrhagic gastritis due to cow's milk allergy is an uncommon diagnosis. Clinical findings in 10 patients (including ours) reported with allergic gastritis were vomiting, malnutrition, anemia, and hematemesis. Gastritis occurs in cow's milk allergy in a wide range of severity, and it could remain hidden in most patients. Unless appropriate management is ensued, patients develop severe malnutrition and severe anemia. Allergic compromise of upper gastrointestinal tract might be considered in all vomiting infants particularly if complicated by hematemesis. Diagnosis of allergic gastritis relies on clinical suspicion helped by endoscopy and gastric biopsies.
Related Concept Videos
Gastritis-II: Pathophysiology
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Gastritis II: Pathophysiology
Peptic Ulcer
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Transcytosis of IgG
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
Allergic Reactions