[Vacuum sealing of extensive wound healing disorders after kidney transplantation]

Area of Science:

• Nephrology
• Transplantation Surgery
• Wound Healing

Background:

• Mycophenolate mofetil (MMF) has improved renal transplant outcomes, reducing acute rejection and enhancing short-term graft survival.
• However, MMF use is associated with surgical complications, particularly delayed wound healing, especially in patients with risk factors like obesity, diabetes, and advanced age.

Purpose of the Study:

• To evaluate the efficacy of the vacuum sealing technique in managing prolonged wound healing complications following renal transplantation in patients treated with MMF.

Main Methods:

• The vacuum sealing technique was applied to two renal transplant recipients experiencing delayed wound healing.
• This method involves applying controlled negative pressure to the wound site.
• Assessment of wound healing progress and feasibility of secondary suture closure was performed.

Main Results:

• The vacuum sealing technique was successfully applied in both cases, promoting granulation tissue formation and wound closure.
• After 15 days of treatment, secondary suture became possible in both patients, indicating successful wound management.
• This demonstrates the technique's potential in addressing MMF-related surgical complications.

Conclusions:

• The vacuum sealing technique offers a viable solution for managing delayed wound healing after renal transplantation, particularly in patients receiving mycophenolate mofetil.
• This approach can facilitate secondary wound closure, potentially improving patient outcomes and reducing the need for prolonged conservative management.