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Updated: Aug 30, 2026

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
Published on: August 11, 2012
[Infection of Chlamydia trachomatis and apoptosis of spermatogenic cells]
Chang-Chun Wan1, Hong Wang, Bao-Jin Hao
1People's Hospital of Jinhu, Jinhu, Jiangsu 211600, China.
Objective:
To evaluate the relationship between infection of Chlamydia Trachomatis(Ct) and apoptosis of spermatogenic cells.
Methods:
Apoptotic spermatogenic cells were examined by Wright-Giemsa staining and the terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate(dUTP)-biotin nick-end labeling(TUNEL) technique.
Results:
Apoptosis rate of Ct infective group was significantly higher than that of normal group(P < 0.01).
Conclusions:
Ct infection may cause the apoptosis of spermatogenic cells, which affords an objective evidence for illustrating the mechanism of Ct-infection-induced male infertility.
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