Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

AAV-based gene transfer.

Hildegard Büning1, Stuart A Nicklin, Luca Perabo

  • 1Laboratorium für Molekulare Biologie Genzentrum Ludwig-Maximilians Universität München 81377 München Germany.

Current Opinion in Molecular Therapeutics
|September 30, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Is the future of cardiac repair cell-free?

European heart journal·2026
Same author

A causal 'lnc' between exercise and ageing in the cardiac vasculature.

European heart journal·2026
Same author

The dark genome in cardiovascular medicine.

European heart journal·2026
Same author

The German National Strategy for Gene- and Cell-Based Therapies: Generating Impact by Employing a Novel Multi-Stakeholder Approach.

Human gene therapy·2026
Same author

In Remembrance of Professor Zelig Eshhar: <i>A Life Committed to CAR-T</i>.

Human gene therapy·2026
Same author

Adiponectin exerts sex-dependent effects on lipid, amino acid, and glucose metabolism during caloric restriction.

PLoS biology·2026

Gene therapy offers promising treatments, but safe and efficient gene delivery is crucial. Adeno-associated viral (AAV) vectors show significant potential for advancing genetic medicine in humans.

Area of Science:

  • Biotechnology
  • Molecular Biology
  • Genetics

Background:

  • Gene therapy is a promising treatment for inherited and acquired diseases.
  • Clinical applications highlight safety concerns in human gene delivery.
  • Efficient and safe gene delivery systems are essential for therapeutic success.

Purpose of the Study:

  • To review recent advancements in gene delivery systems for human gene therapy.
  • To evaluate the potential of adeno-associated viral (AAV) vectors in genetic medicine.
  • To underscore the importance of vector selection for safety and efficiency.

Main Methods:

  • Review of current literature on gene therapy and viral vectors.
  • Analysis of safety and efficiency data from clinical gene therapy trials.

Related Experiment Videos

  • Focus on adeno-associated viral (AAV) vector technology.

    • Main Results:

    • Recent developments indicate significant progress in gene delivery technologies.
    • Adeno-associated viral (AAV) vectors possess unique characteristics for gene therapy.
    • Safety and efficiency are key considerations in vector selection.

    Conclusions:

    • Adeno-associated viral (AAV) vectors are poised to be pivotal in future genetic medicine.
    • Careful selection of gene delivery systems is fundamental for safe and effective gene therapy.
    • Continued research into AAV vectors will drive the deployment of genetic medicine.