Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Autoimmunity in the peripheral nervous system.

Angelo Quattrini1, Stefano C Previtali, Bernd C Kieseier

  • 1Dept. of Neurology, San Raffaele Scientific Institute, Milano, Italy. a.quattrini@hsr.it

Critical Reviews in Neurobiology
|September 30, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Perspective and quality of life in amyotrophic lateral sclerosis patients undergoing percutaneous endoscopic gastrostomy.

Frontiers in nutrition·2026
Same author

Tolerability, Safety and Effectiveness of Sigh Introduction During Non-Invasive Mechanical Ventilation Cycles in Patients With Amyotrophic Lateral Sclerosis.

European journal of neurology·2026
Same author

Regulation of Schwann Cell-Axon Interactions in Nerve Development: The Role of Slit2 in Axonal Sorting.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same author

Increased CSF levels of soluble AXL at diagnosis correlate with poor prognosis in patients affected by amyotrophic lateral sclerosis.

Brain communications·2026
Same author

Prostaglandin D2 Synthase Controls Schwann Cells Metabolism and Peripheral Myelin Homeostasis.

Glia·2026
Same author

The genetic architecture of primary lateral sclerosis in a cohort of Italian patients.

Journal of neurology·2025

Autoimmune disorders affecting the peripheral nervous system (PNS) involve complex immune responses causing significant disability. This review details neuroimmune interactions and their role in PNS autoimmune diseases.

Area of Science:

  • Neuroimmunology
  • Peripheral Nervous System Disorders
  • Autoimmune Diseases

Background:

  • Autoimmune disorders of the peripheral nervous system (PNS) are a diverse group of conditions.
  • These diseases stem from abnormal immune responses, often leading to severe morbidity and mortality.
  • Despite unknown etiology, understanding of pathophysiological mechanisms causing tissue damage is growing.

Purpose of the Study:

  • To describe molecular components of neuroimmune interactions in PNS autoimmune disorders.
  • To elucidate the function of these components in disease pathogenesis.
  • To review clinical, pathological, diagnostic, and therapeutic aspects of these conditions.

Main Methods:

  • Review of current literature on neuroimmune interactions.

Related Experiment Videos

  • Analysis of molecular mediators involved in cell-cell and cell-extracellular-matrix interactions.
  • Inclusion of insights from animal models and genetic approaches.

    • Main Results:

    • Identification of key molecular mediators in neuroimmune interactions.
    • Understanding of how these mediators contribute to dysfunction and damage in PNS autoimmune diseases.
    • Comprehensive overview of clinical and pathological features.

    Conclusions:

    • Enhanced understanding of neuroimmune interactions is crucial for addressing PNS autoimmune disorders.
    • Knowledge of molecular mechanisms aids in diagnosing and treating these debilitating conditions.
    • Further research into these pathways promises improved therapeutic strategies.