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Updated: Aug 30, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
Published on: August 15, 2025
Olanzapine for recurrent aggression in a patient with temporal lobe epilepsy who had temporal lobectomy
Jaime E C Hallak1, Serdar M Dursun, Ricardo Guarnieri
1Department of Neuropsychiatry and Medical Psychology, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. jaime.hallak@man.ac.uk
Abstract:
We report the case of a patient with epilepsy who had interictal severe affective aggression, and whose epilepsy significantly improved (but not aggression) after successful temporal lobectomy. Olanzapine significantly improved these aggressive episodes refractory to neurosurgery and previous pharmacological treatments including antipsychotics, anticonvulsants/mood stabilizers and benzodiazepines.
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