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Updated: Aug 30, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Single-stage treatment of aortic coarctation and aortic valve disease
Li Zhong Sun1, Xin Jin Luo, Yong Min Liu
1Department of Cardiovascular Surgery, Fu Wai Hospital, Peking Union Medical College, Beijing, People's Republic of China.
Insights
Simultaneous surgical repair of thoracic aortic coarctation and severe aortic valve disease using an extraanatomic bypass is safe and effective. This single-stage approach reduces morbidity and mortality compared to staged procedures for complex aortic complications.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Vascular Surgery
Background:
- Surgical management of thoracic aortic coarctation combined with severe aortic valve disease presents significant challenges.
- Staged surgical procedures for these combined conditions are linked to increased morbidity and mortality rates.
Purpose of the Study:
- To evaluate the safety and efficacy of a simultaneous, single-stage surgical approach for patients with thoracic aortic coarctation and severe aortic valve disease.
- To assess the outcomes of combining ascending aorta-infrarenal abdominal aorta bypass graft with aortic valve replacement.
Main Methods:
- A cohort of 9 patients (8 males, 1 female; mean age 30.1 years) underwent simultaneous ascending aorta-infrarenal abdominal aorta bypass graft and aortic valve replacement between 1997 and 2001.
- The study focused on the outcomes of this combined, single-stage procedure.
Main Results:
- Eight of the nine patients survived the procedure with successful correction of the underlying pathology.
- Postoperative outcomes included reduced upper limb blood pressure and increased lower limb blood pressure in survivors.
- One perioperative death occurred due to extracorporeal circulation failure, and one patient experienced a transient intestinal obstruction.
Conclusions:
- The single-stage approach utilizing an extraanatomic bypass is a safe and effective strategy for managing complex aortic complications involving coarctation and severe aortic valve disease.
- This method simplifies management and offers a favorable alternative to staged interventions for these challenging conditions.
Abstract:
Surgical management of thoracic aortic coarctation associated with severe aortic valve disease is difficult in most cases. As staged procedures are associated with a higher rate of morbidity and mortality, simultaneous operative management of both lesions is desirable. From 1997 to 2001, 9 patients (8 males and 1 female with a mean age of 30.1 +/- 10.4 years) with this condition underwent simultaneous ascending aorta-infrarenal abdominal aorta bypass graft and aortic valve replacement. One patient died from failure of the extracorporeal circulation during the operation. Another patient suffered from partial intestinal obstruction in the early postoperative period but was successfully treated. The underlying pathology was successfully corrected in the 8 surviving patients, whose blood pressure in the upper limbs was reduced while that in the lower limbs rose. Being easier to manage, the single-stage approach with extraanatomic bypass is safe and effective for managing this aortic complication.
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