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Updated: Aug 30, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
[Psychologic aspects in perinatal medicine 1980-2000: I. Pregnancy]
1Ustav pro péci o matku a dítĕ, Praha.
Insights
Psychosocial factors significantly impact pregnancy outcomes, with evolving concerns from smoking and obesity to HIV/AIDS and drug dependency. Understanding these influences is crucial for healthy new generations.
Area of Science:
- Perinatal health
- Psychosocial epidemiology
- Maternal and child health
Context:
- Retrospective analysis of psychosocial factors in pregnancy (1980-2000).
- Background study for "Evaluation of the Development, Present State and Conditions to Provide Healthy Physical, Mental and Social Development of the New Generation until 2010."
- Focus on the "Healthy Physical, Mental and Social Development of the New Generation" framework.
Purpose:
- To review the fulfillment of prognosis regarding psychosocial influences on conceptus development.
- To analyze the evolution of psychosocial risk factors and their relationship with biological factors in pregnancy.
- To identify emerging psychosocial challenges in pregnant populations.
Summary:
- Perinatal studies increasingly recognized psychosocial risk factors alongside biological ones from the 1980s.
- The 1990s saw the emergence of new challenges including pregnant women with HIV/AIDS, drug dependency, and those undergoing artificial fertilization.
- Psychoprophylactic preparation for delivery has evolved, with considerations for paternal presence and the psychological impact of medical examinations.
Impact:
- Highlights the evolving landscape of psychosocial challenges in pregnancy care.
- Emphasizes the need to address both medical and psychosocial aspects for maternal and infant well-being.
- Informs future research and interventions for healthy child development.
Objective:
A retrospective view of fulfillment of prognosis concerning psychosocial influence on the development of conceptus within the framework of the "Healthy Physical, Mental and Social Development of the New Generation" (11) as a background work for a new project called "Evaluation of the Development, Present State and Conditions to Provide Healthy Physical, Mental and Social Development of the New Generation until 2010" (No. 7346-3).
Type Of The Study:
A retrospective analysis of the period 1980-2000, dealing with psychosocial problems in relation to pregnancy in this country. NAME AND ADDRESS OF THE INSTITUTION: Institute of the Care for Mother and Child, Podolské nábrezí 157, 147 00, Praha 4.
Conclusion:
In the beginning of eighties, the perinatal studies paid for the first time attention to psychosocial risk factors and their close relationship to the biological risk factors. For example, smoking and obesity in women occurred at significantly higher rates in dysfunctional families as well as artificial abortions, perinatal losses etc. In the nineties epidemiological studies in this area were originated. New problem areas, which emerged, concerned mainly pregnant women with HIV/AIDS infection, drug-dependent women and those after artificial fertilization. In addition to medial questions, social and psychological questions had also to be solved. An old and new theme is a psychoprophylactic preparation for delivery, which underwent significant changes, particularly in connection with presence of the father during delivery. Moreover, it should not be neglected to investigate to influence of the methods of examination on the psychical conditions of the pregnant women for their possible negative effects, as in for example the case of examination of amniotic fluid sampled by amniocentesis for genetic indication and a "long" period of waiting for the results. In contrast, other factors may exert a positive effect, as is for example the case with sonographic examination of the conceptus, when the women can observe the conceptus and its movements on the screen.
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