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Updated: Aug 30, 2026
Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[A pathologic analysis on 9,666 cases of tumors of nose, pharynx and throat]
Yu-cheng Xie1, Wei-ping Liu, Yu-mei Jiang
1Department of Pathology, West-China Hospital of Sichuan University, Chengdu 610041, China.
Objective:
To analyze nasal, pharyngeal and laryngeal tumor patients age, sex and tumors' sites, to find out the relationship of above indices and tumor's pathologic types.
Methods:
9,666 cases of tumors on nose, pharynx and throat diagnosed in West-China Hospital in 1984 to 1999 were analyzed for the constitution of histological type.
Results:
1. the ratio of benign and malignant tumor is 1:8.6, it is 1:62.0 in nasalpharynx; 2. papilloma, angiofibroma and angioma are more commonly seen in all 21 kinds of benign tumors; 3. differentiated squamous cell carcinoma, non-keratinized is the most common types in 25 kinds of malignant tumors, the ratio of carcinoma and sarcoma is 11.98 to 1; 4. The average age of patients with malignancy is about 10 years older than that of the patients with benign tumors, and malignant patients are male predominant; 5. squamous cell papilloma of oralpharynx was the most common in all benign tumors; nasopharyngeal carcinoma is the most common in all malignancies, nasal lymphomas are the most common seen sarcoma.
Conclusion:
The histologic types of nasal, pharyngeal and laryngeal tumors are related with patients' age, sex and sites of tumors.
