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Updated: Jul 24, 2026

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Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development

David R Natale1, Andrew J Watson

  • 1Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada N6A 5C1.

Mechanisms of Development
|October 1, 2003
PubMed

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Cadherins in Tissue Organization

The cadherins are a superfamily of cell adhesion molecules comprising over 180 variants, with specific tissues expressing a particular combination of cadherin types. Cadherins generally exhibit homophilic binding; i.e., cadherins on one cell bind to cadherins of the same or closely related type on another cell. Thus, cells of the same type have a specific affinity to bind to each other and sort themselves into clusters to form tissues.
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