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Published on: March 10, 2016
Inverted papilloma of the nose and paranasal sinuses in children
A J D'Angelo1, A Marlowe, F I Marlowe
1Division of Otolaryngology, Head and Neck Surgery, Medical College of Pennsylvania, Philadelphia 19129.
Insights
Inverted papillomas, rare nasal tumors in children, share aggressive traits with adult cases, including recurrence and malignant changes. Effective treatment involves wide surgical excision and lifelong monitoring for these pediatric sinonasal neoplasms.
Area of Science:
- Otolaryngology
- Pediatric Oncology
- Surgical Pathology
Background:
- Inverted papillomas (IPs) are uncommon neoplasms affecting the nasal cavity and paranasal sinuses.
- While frequently diagnosed in adults, their occurrence in children presents unique challenges due to potential for aggressive behavior.
Observation:
- Pediatric sinonasal inverted papillomas exhibit biological characteristics similar to adult counterparts.
- These include a notable frequency of tumor recurrence and the potential for malignant transformation.
Findings:
- Treatment strategies effective in adults are recommended for pediatric inverted papillomas.
- This includes wide surgical excision and thorough histopathological examination of excised tissue.
Implications:
- Radiation therapy is reserved for inverted papillomas associated with carcinoma.
- Lifelong follow-up is essential due to the possibility of late recurrences in pediatric inverted papilloma patients.
Abstract:
Inverted papillomas are rare nasal and sinus neoplasms in children. The disturbing biological characteristics of these tumors seen in adults, including malignant degeneration and the high frequency of recurrence, have been similarly observed in the pediatric population. Therefore, inverted papilloma in children mandates similar treatment to that proven effective in adults, including wide excision and careful histopathological examination of any tissue excised. Radiation therapy should be reserved for those tumors associated with carcinoma. Since recurrences can occur after long periods of time, life-long follow-up is warranted.
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