Scleral nodule associated with sarcoidosis
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Updated: Aug 30, 2026
Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Faqir A Qazi1, Jennifer E Thorne, Douglas A Jabs
1Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Purpose:
To describe an unusual case of an inflammatory scleral nodule associated with systemic sarcoidosis.
Design:
Observational case report.
Methods:
A patient presented with a red, painful, elevated scleral nodule on the left eye that was unresponsive to nonsteroidal anti-inflammatory drugs and topical corticosteroids.
Results:
Laboratory evaluation was normal with the exception of elevated liver function tests. Further evaluation by a gastroenterologist revealed a granulomatous hepatitis secondary to sarcoidosis, which was confirmed by liver biopsy. Treatment with oral prednisone resulted in resolution of the hepatitis and scleral nodule. The patient has been recurrence-free over 7 months of follow-up.
Conclusion:
Although rare, scleral disease may be associated with sarcoidosis.
