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Updated: Aug 30, 2026

09:16
Orthotopic Small Bowel Transplantation in Rats
Published on: November 6, 2012
[Allogenic small intestine transplantation in the rat model with initial CsA therapy: first detection of Th2-induced
R Gieseler1, J H Peters, R Schlemminger
1Abteilung für Immunologie, Universitätskliniken Göttingen, Georg-August-Universität, D-37075 Göttingen.
Abstract:
It is not clear how initial therapy with CsA effects indefinite allograft acceptance after small bowel transplantation in the rat. Our study of post-transplant alterations of immune parameters within donor-type mesenteric lymph nodes suggests CsA-dependent, Th2-mediated induction of graft-specific T-cell tolerance.

