Related Experiment Video
Updated: Aug 30, 2026

Intrathecal Vector Delivery in Juvenile Rats via Lumbar Cistern Injection
Published on: March 29, 2024
Intrathecal drug delivery 2002
1Pediatric Neurosurgery, Indianapolis Neurosurgical Group, Inc., IN, USA. TurnerLah@aol.com
Background:
Intrathecal drug delivery has been used clinically since the 1970's. Significant clinical advances have been made combining new technology with pharmacology and surgery. Continuous infusion of medication for both analgesia and spasticity has become a part of the armamentarium for specialists in these areas. Significant recent advances in technology promise further enhancements and improvements for intrathecal therapy.
Methods:
A review of the literature combined with 20 years personal experience with intrathecal drug delivery.
Findings/Discussion:
Intrathecal therapy has established a role in the treatment of malignant pain, benign pain and severe spasticity. Significant literature and the current state of practice in the United States are reviewed. Recent therapeutic enhancements are discussed, and a wish list of future technological enhancements presented.
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