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The random blood glucose level, a risk factor for mortality after acute myocardial infarction, in non-diabetic

A S Mane1, P McHugh, J Conneely

  • 1General Hospital, Roscomon, Ireland. manesaras@yahoo.com

Irish Medical Journal
|October 2, 2003
PubMed

Insights

In non-diabetic patients, higher blood glucose levels after acute myocardial infarction are linked to increased mortality risk within two years. This association was particularly noted in anterior wall infarction and female heart failure patients.

Area of Science:

  • Cardiology
  • Endocrinology
  • Public Health

Background:

  • The link between blood glucose and cardiovascular events is established in diabetics.
  • The prognostic value of admission glucose in non-diabetic post-myocardial infarction (MI) patients requires further investigation.

Purpose of the Study:

  • To retrospectively analyze the correlation between admission random venous glucose levels and all-cause mortality in non-diabetic patients following their first acute myocardial infarction.

Main Methods:

  • Fifty-three non-diabetic patients (30 male, 23 female) admitted for acute MI were studied.
  • Random venous glucose was measured on admission and correlated with all-cause mortality over two years.

Main Results:

  • Thirteen patients died and 40 survived within the two-year follow-up period.
  • Patients who died had significantly higher mean blood glucose levels (8.62 mmol/L) compared to survivors (6.69 mmol/L).
  • Elevated glucose levels showed a stronger association with mortality in anterior wall MI and in female patients with heart failure.

Conclusions:

  • Higher admission blood glucose levels in non-diabetic patients are associated with increased two-year all-cause mortality after a first acute myocardial infarction.
  • Admission glucose may serve as a prognostic marker in this patient population.

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