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Related Experiment Videos

Gender differences in perception of PAD: a pilot study.

Roberta K Oka1, Andrzej Szuba, John C Giacomini

  • 1School of Nursing, University of California at Los Angeles, CA 90095-6918, USA. roka@sonnet.ucla.edu

Vascular Medicine (London, England)
|October 2, 2003
PubMed
Summary
This summary is machine-generated.

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Peripheral arterial disease (PAD) significantly impacts quality of life, especially for women. Claudication affects women more due to increased pain and mood disturbances, despite similar disease severity.

Area of Science:

  • Cardiovascular Medicine
  • Quality of Life Research
  • Health Disparities

Background:

  • Peripheral arterial disease (PAD) profoundly limits quality of life (QoL) in patients.
  • Claudication, a key symptom of PAD, negatively affects QoL, but influencing factors remain unclear.
  • Understanding QoL determinants in PAD, particularly sex-based differences, is crucial for targeted interventions.

Purpose of the Study:

  • To evaluate the impact of claudication on QoL in patients with PAD.
  • To investigate potential sex-based differences in QoL and its determinants among PAD patients.

Main Methods:

  • Cross-sectional study involving 71 men and 26 women with PAD and claudication.
  • Assessed disease severity using ankle-brachial index (ABI) and community-based walking.

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  • Evaluated QoL domains, including physical functioning, bodily pain, and mood disturbance.

    • Main Results:

    • Disease severity (ABI, walking) and PAD prevalence were similar between men and women.
    • Women reported significantly worse physical functioning (p=0.01), increased bodily pain (p=0.04), and greater mood disturbance (p=0.012) than men.
    • Men reported higher rates of comorbid conditions.

    Conclusions:

    • Claudication and PAD have a disproportionately greater negative impact on women's QoL compared to men.
    • Higher prevalence of mood disturbance and bodily pain in women may explain the greater QoL impact.
    • Sex-specific factors influence QoL outcomes in PAD patients, necessitating tailored care strategies.