Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Acute hepatitis E with elevated creatine phosphokinase.

Takatoshi Kitazawa1, Yasuo Ota, Mizuho Suzuki

  • 1Department of Infectious Disease, Graduate School of Medicine, The University of Tokyo, Tokyo.

Internal Medicine (Tokyo, Japan)
|October 2, 2003
PubMed
Summary

Acute hepatitis E, often seen in developing nations, is rising in Japan due to travel. A recent case showed elevated creatine phosphokinase, suggesting a potential link to this liver infection.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Endoscopic trimming of a migrated gastroduodenal stent using a loop cutter and a two-channel endoscope.

Endoscopy·2014
Same author

Multiple metal stenting using a double-balloon endoscope for malignant biliary obstruction in a patient with hepaticojejunostomy.

Endoscopy·2014
Same author

Scheduled second-look endoscopy is not recommended after endoscopic submucosal dissection for gastric neoplasms (the SAFE trial): a multicentre prospective randomised controlled non-inferiority trial.

Gut·2014
Same author

Circulating AIM as an indicator of liver damage and hepatocellular carcinoma in humans.

PloS one·2014
Same author

Total cholesterol level for assessing pancreatic insufficiency due to chronic pancreatitis.

Gut and liver·2014
Same author

TOKYO criteria 2014 for transpapillary biliary stenting.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society·2014

Area of Science:

  • Hepatology
  • Virology
  • Clinical Medicine

Background:

  • Acute hepatitis E is caused by the hepatitis E virus (HEV), endemic in developing countries.
  • Increasing international travel has led to a rise in HEV cases in non-endemic regions like Japan.
  • Understanding HEV's clinical manifestations is crucial for diagnosis and management.

Observation:

  • A case study of a Japanese man with acute hepatitis E following travel to south China is presented.
  • The patient exhibited elevated serum creatine phosphokinase (CPK) levels upon admission.
  • Muscle damage symptoms were absent, with CPK isoenzyme MM comprising 100% of the elevated level.

Findings:

  • Serum CPK levels normalized as the hepatitis resolved, indicating a potential association with acute hepatitis E.

Related Experiment Videos

  • This observation suggests that elevated CPK may be a biochemical marker in HEV infection.
  • Further investigation is needed to confirm if muscle involvement is characteristic of acute hepatitis E.

    • Implications:

    • Elevated CPK could serve as a diagnostic indicator in acute hepatitis E cases.
    • Distinguishing HEV from other viral hepatitis (A, B, C) is important, as clinical presentations may differ.
    • This finding warrants further research into the specific mechanisms and prevalence of CPK elevation in various viral hepatitis infections.