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Rhinitis in pre-school children: prevalence, association with allergic diseases and risk factors
D G Peroni1, G L Piacentini, L Alfonsi
1Department of Paediatrics, University of Verona, Verona, Italy. peroni.diego@tiscalinet.it
Insights
Rhinitis is common in preschoolers and strongly linked to asthma and eczema. Allergic sensitization is a key risk factor, highlighting the need for early evaluation in children.
Area of Science:
- Pediatric Allergy and Immunology
- Epidemiology of Respiratory Diseases
- Environmental Health in Children
Background:
- Rhinitis symptoms like sneezing and nasal congestion are prevalent in preschool children, distinct from common colds.
- Understanding risk factors and associations with allergic diseases is crucial for early intervention.
Purpose of the Study:
- To determine the prevalence of rhinitis in preschool children.
- To identify risk factors associated with rhinitis.
- To explore the relationship between rhinitis, allergic diseases, and sensitization.
Main Methods:
- Utilized the International Study of Asthma and Allergies in Childhood (ISAAC) written questionnaire (WQ) administered to parents of 3-5 year olds.
- Randomly selected 18 nursery schools for participation.
- Assessed allergic sensitization via skin prick tests (SPT) and analyzed data using chi2 tests.
Main Results:
- Rhinitis prevalence was 16.8% in the past 12 months.
- Rhinitic children showed significantly higher rates of asthma, wheezing, atopic dermatitis, and allergic sensitization.
- Risk factors included sensitization to grass pollen and house dust mites, family history of atopy, pets, male gender, and older age.
Conclusions:
- Rhinitis in preschoolers is significantly associated with wheezing, asthma, and atopic dermatitis.
- Allergic sensitization is a notable risk factor for rhinitis in this age group.
- Evaluation for allergic sensitization is recommended for preschool children presenting with rhinitis.
Background:
The aim of our study was to assess the prevalence of rhinitis, sneezing, runny or blocked nose apart from colds in a pre-school children population and to evaluate the risk factors and relationship with allergic diseases and sensitization.
Methods:
Eighteen nursery schools were randomly selected. The International Study of Asthma and Allergies in Childhood (ISAAC) written questionnaire (WQ) was distributed and filled by parents of pre-school children (3-5 years). The allergic sensitization to common aeroallergens and foods was evaluated by skin prick test (SPT). chi2 tests were used to compare proportions between rhinitic and non-rhinitic children.
Results:
One thousand four hundred and two (92%) valuable questionnaires were returned. Prevalence of rhinitis in the last 12 months was 16.8%. Rhinitic children compared to non-rhinitic children presented a significant increase of diagnosed asthma (20.8% vs. 6.2%, P<0.001), lifetime wheezing (43.2% vs. 21.6%, P<0.001), wheezing in the last 12 months (25.0% vs. 9.4%, P<0.001), atopic dermatitis (22.9% vs. 13.9%, P<0.001) and allergic sensitization (29.9% vs. 13.7%, P<0.001). Sensitization to grass pollen and house dust mites were significant risk factors for rhinitis (P<0.01). A family history of atopy, having pets at home, male gender and greater age were significant risk factors for rhinitis, but not smoking exposure, sharing a bedroom or breastfeeding.
Conclusions:
In pre-school children rhinitis has a strong association with wheezing symptoms, asthma and atopic dermatitis. Allergic sensitization is a risk factor for rhinitis and should be evaluated even in pre-school children.
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