Oral-motor patterns of rhythmic trigeminal activity generated in fetal rat brainstem in vitro
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Updated: Aug 30, 2026

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Preparation of Rhythmically-active In Vitro Neonatal Rodent Brainstem-spinal Cord and Thin Slice
Published on: March 23, 2019
Kohji Ishihama1, Mikihiko Kogo, Hidehiko Koizumi
1First Department of Oral & Maxillofacial Surgery, Osaka University Graduate School of Dentistry, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.
Brain Research. Developmental Brain Research
|October 2, 2003
Abstract:
Development of neural circuits generating fetal oral-motor activity was characterized in an in vitro isolated brainstem block preparation. Rhythmical trigeminal activity (RTA) at E20-E21 resembled either the pattern or rhythm of neonatal RTA. Conversely, at E18-E19, RTA displayed a different pattern of discharge from neonatal RTA, and output was not regular but intermittent with another slow rhythm.

