Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cryptococcal Meningitis

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...

Respiratory Syncytial Virus Disease

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...

Cytomegalovirus Disease

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

Vaccinations

Vaccinations

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Glucagon-like Peptide-1 Receptor Agonists and Risk for Anterior Ischemic Optic Neuropathy : A Nationwide Cohort Study.

Annals of internal medicine·2026

Same author

Survival Following Neoplastic Disease in Individuals With Neurofibromatosis 1-A National Danish Population-Based Cohort Study.

International journal of cancer·2026

Same author

Letter to the editor "Utilization patterns and determinants of guideline-recommended therapies for acute heart failure in Denmark".

European heart journal. Acute cardiovascular care·2026

Same author

A structural equation modeling framework for estimating symptom burden based on symptom clusters in cancer survivors.

Scientific reports·2026

Same author

Acute SARS-CoV-2 infection and self-reported post-acute cognitive dysfunctions from the Danish EFTER-COVID survey.

Communications medicine·2026

Same author

Initiation of eplerenone vs. spironolactone and all-cause mortality in HFrEF: linked database study.

European heart journal. Cardiovascular pharmacotherapy·2026

Search research articles

Related Experiment Video

Updated: Jun 14, 2026

The Adjuvant Efficacy of Angong Niuhuang Pill in the Treatment of Viral Encephalitis: A Meta-Analysis of Randomized Controlled Trials

The Adjuvant Efficacy of Angong Niuhuang Pill in the Treatment of Viral Encephalitis: A Meta-Analysis of Randomized Controlled Trials

Published on: April 19, 2024

Association between thimerosal-containing vaccine and autism.

Anders Hviid¹, Michael Stellfeld, Jan Wohlfahrt

¹Danish Epidemiology Science Centre, Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark. aii@ssi.dk

|October 2, 2003

Summary

This study found no link between thimerosal-containing vaccines and autism. Research on ethylmercury in vaccines indicates no causal relationship with autistic-spectrum disorders in children.

More Related Videos

Positron Emission Tomography Using 64-Copper as a Tracer for the Study of Copper-Related Disorders

Positron Emission Tomography Using 64-Copper as a Tracer for the Study of Copper-Related Disorders

Published on: April 28, 2023

Using the Visual World Paradigm to Study Sentence Comprehension in Mandarin-Speaking Children with Autism

Using the Visual World Paradigm to Study Sentence Comprehension in Mandarin-Speaking Children with Autism

Published on: October 3, 2018

Related Experiment Videos

Last Updated: Jun 14, 2026

The Adjuvant Efficacy of Angong Niuhuang Pill in the Treatment of Viral Encephalitis: A Meta-Analysis of Randomized Controlled Trials

The Adjuvant Efficacy of Angong Niuhuang Pill in the Treatment of Viral Encephalitis: A Meta-Analysis of Randomized Controlled Trials

Published on: April 19, 2024

Positron Emission Tomography Using 64-Copper as a Tracer for the Study of Copper-Related Disorders

Positron Emission Tomography Using 64-Copper as a Tracer for the Study of Copper-Related Disorders

Published on: April 28, 2023

Using the Visual World Paradigm to Study Sentence Comprehension in Mandarin-Speaking Children with Autism

Using the Visual World Paradigm to Study Sentence Comprehension in Mandarin-Speaking Children with Autism

Published on: October 3, 2018

Area of Science:

Neuroscience
Immunology
Pediatrics

Background:

Thimerosal, an ethylmercury-containing preservative in vaccines, has raised concerns regarding potential links to neurodevelopmental disorders.
Mercuric compounds are known for their nephrotoxic and neurotoxic effects at high doses.

Purpose of the Study:

To investigate the association between vaccination with thimerosal-containing vaccines and the development of autism and other autistic-spectrum disorders.
To determine if there is a dose-response relationship between ethylmercury exposure from vaccines and autistic-spectrum disorders.

Main Methods:

A population-based cohort study was conducted in Denmark, including 467,450 children born between 1990 and 1996.
Children vaccinated with thimerosal-containing vaccines were compared to those who received thimerosal-free formulations of the same vaccines.
Autism and autistic-spectrum disorders were assessed, with analysis of rate ratios and dose-response trends for ethylmercury.

Main Results:

No significant difference in the risk of autism or other autistic-spectrum disorders was observed between children who received thimerosal-containing vaccines and those who received thimerosal-free vaccines.
The study found no evidence of a dose-response association between the amount of ethylmercury received and the risk of developing autism or other autistic-spectrum disorders.
Rate ratios for autism were 0.85 (95% CI, 0.60-1.20) and for other autistic-spectrum disorders were 1.12 (95% CI, 0.88-1.43).

Conclusions:

The findings do not support a causal relationship between childhood vaccination with thimerosal-containing vaccines and the development of autistic-spectrum disorders.
This research contributes to the understanding of vaccine safety and neurodevelopmental outcomes.