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Related Experiment Videos

[Fetal plexus cysts. An indication for prenatal karyotyping].

W Werner-von der Burg1, W Hatzmann, K Kuchenbecker

  • 1Marienhospital Witten.

Geburtshilfe Und Frauenheilkunde
|November 1, 1992
PubMed
Summary

Fetal choroidal plexus cysts, detected via ultrasound, are often transient. However, bilateral cysts may indicate an increased risk for chromosomal abnormalities like trisomy 18 or 21.

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Area of Science:

  • Obstetrics and Gynecology
  • Fetal Medicine
  • Diagnostic Ultrasound

Background:

  • Routine pregnancy monitoring and diagnostic clarification of unclear sonographic findings are crucial for fetal well-being.
  • Ultrasound technology, utilizing convex and vaginal transducers, plays a vital role in prenatal diagnostics.

Observation:

  • A study examined 1844 pregnant patients between March 1988 and September 1990.
  • Fetal choroidal plexus cysts were identified in 13 cases (0.7%), with 6 unilateral and 7 bilateral occurrences.
  • Most cysts were diagnosed between 13 and 22 weeks of gestation.

Findings:

  • Unilateral choroidal plexus cysts were transient, small, and resolved by 24 weeks gestation.
  • Of the 7 cases with bilateral cysts, 4 fetuses had no other anatomical abnormalities.

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  • Three fetuses with bilateral cysts exhibited further anatomical abnormalities, including two cases of trisomy 18 and one case of trisomy 21.

    • Implications:

    • Transient unilateral choroidal plexus cysts are generally benign findings.
    • Bilateral choroidal plexus cysts warrant further investigation due to a potential association with chromosomal abnormalities.
    • Early detection of fetal anomalies through ultrasound aids in timely genetic counseling and management.