Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Drug-induced pseudotumor cerebri.

A B M Salah Uddin1

  • 1New Jersey Neuroscience Institute at JFK Medical Center, 65 James Street, Edison, NJ 08818, USA. auddin@solarishs.org

Clinical Neuropharmacology
|October 2, 2003
PubMed
Summary

Pseudotumor Cerebri (PTC) is a rare disorder. A case study shows switching antiepileptic drugs from divalproate to topiramate can resolve PTC symptoms in patients with epilepsy.

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Limb shaking transient ischemic attack--an unusual presentation of carotid occlusive disease. A case report and review of the literature.

Parkinsonism & related disorders·2004
Same author

A unilateral presentation of 'Satoyoshi syndrome'.

Parkinsonism & related disorders·2002
See all related articles

Area of Science:

  • Neurology
  • Ophthalmology

Background:

  • Pseudotumor Cerebri (PTC) is an idiopathic intracranial hypertension disorder.
  • Known associations include steroid withdrawal, hypervitaminosis A, and tetracyclines.

Observation:

  • A patient with a seizure disorder on chronic divalproex therapy developed PTC.
  • Symptoms included new-onset headaches and visual disturbances.

Findings:

  • Changing antiepileptic medication from divalproate to topiramate resulted in PTC symptom remission.
  • Seizure control was maintained with topiramate.

Implications:

  • Consider PTC diagnosis in patients on divalproate experiencing new or worsening headaches, especially with visual changes.
  • Prompt diagnosis and medication adjustment may prevent permanent vision loss.