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Updated: Aug 30, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
[Non cardiac surgery in patient with coronary stenting: think sirolimus now!]
M H Fléron1, M Dupuis, P Mottet
1Département d'anesthésie-réanimation, groupe hospitalier Pitié-Salpêtrière, 75013 Paris, France. mh.fleron@psl.ap-hop-paris.fr
Insights
A patient experienced severe cardiogenic shock before breast surgery due to sirolimus-eluting stent thrombosis. Successful percutaneous transluminal coronary angioplasty and supportive care led to recovery, highlighting surgical timing and antiplatelet management needs.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Interventional Cardiology
Background:
- Cardiogenic shock is a life-threatening condition often requiring immediate intervention.
- Sirolimus-eluting stents are commonly used for coronary artery disease but carry a risk of thrombosis.
- Preoperative cardiogenic shock in patients undergoing non-cardiac surgery is rare and poses significant management challenges.
Observation:
- A patient presented with severe cardiogenic shock prior to scheduled breast surgery.
- The shock was attributed to acute thrombosis of two sirolimus-eluting stents implanted three months earlier.
- This clinical scenario highlights a critical intersection of cardiovascular events and elective surgical procedures.
Findings:
- Percutaneous transluminal coronary angioplasty (PTCA) was successfully performed to address the stent thrombosis.
- The patient received intensive medical management, including intra-aortic balloon counter pulsation and dobutamine infusion.
- Recovery was rapid, with the patient responding well to the 1-day treatment regimen.
Implications:
- The case underscores the importance of carefully considering the timing of elective surgery in patients with recent coronary stent placement.
- Optimal management strategies for shifting antiplatelet therapy in this high-risk population require further discussion and consensus.
- This case provides valuable insights into managing complex cardiovascular complications in the perioperative setting.
Abstract:
We describe a severe preoperative cardiogenic shock in a patient scheduled for a breast surgery. The cardiogenic shock was in relation with thrombosis of two sirolimus-eluting stents received 3 months ago. A percutaneous transluminal coronary angioplasty was successfully performed. The patient recovered well after a 1-day treatment including intraaortic balloon counter pulsation and dobutamine infusion. We discuss about the ideal timing to plan surgery and how to manage the shift of antiplatelet agents.
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