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Related Experiment Videos

Optic nerve sheath meningiomas.

Peerooz Saeed1, Jack Rootman, Robert A Nugent

  • 1Department of Ophthalmology, University of British Columbia and the Vancouver General Hospital, 2550 Willow Street, Vancouver, British Columbia, Canada V5Z 3N9.

Ophthalmology
|October 3, 2003
PubMed
Summary
This summary is machine-generated.

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Optic nerve sheath meningiomas grow slowly and typically affect middle-aged women. Conservative management is often best, with radiotherapy for worsening vision and en bloc excision for surgical cases.

Area of Science:

  • Ophthalmology
  • Neurology
  • Oncology

Background:

  • Optic nerve sheath meningiomas (ONSMs) are primary intracranial tumors.
  • Understanding their natural history and management is crucial for visual preservation.

Purpose of the Study:

  • To investigate the natural history and growth patterns of ONSMs.
  • To evaluate the outcomes of various management strategies for ONSMs.

Main Methods:

  • Retrospective case series of 88 patients treated between 1976 and 1999.
  • Review of clinical, imaging, and histopathologic data.

Main Results:

  • ONSMs typically present in middle-aged females with visual loss; calcification correlated with slower growth.

Related Experiment Videos

  • Posterior orbital tumors and younger patients showed increased intracranial involvement and growth rates.
  • Radiotherapy improved vision and halted tumor growth; en bloc excision prevented recurrence, unlike debulking.

    • Conclusions:

    • ONSMs exhibit indolent growth, favoring conservative management.
    • Radiotherapy is recommended for progressive visual decline.
    • En bloc tumor excision is the preferred surgical approach to prevent recurrence.