Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Osteoarticular tuberculosis in children.

S B Singh1, S K Saraf, L I Singh

  • 1Department of Orthopedics, Banaras Hindu University, Varanasi.

Indian Pediatrics
|September 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dynamic system reliability under external shocks and internal markovian degradation.

Scientific reports·2026
Same author

Exploring Medical Students' Level of Empathy and its Correlation with Prosocial Behaviour in Jharkhand, India.

Kathmandu University medical journal (KUMJ)·2026
Same author

Stakeholder's Perspectives on the Barriers and Facilitators of Childhood Cancer Care in India.

Indian pediatrics·2025
Same author

Evaluation of Yograj Guggulu, Ashwagandha Churna and Narayana Taila in management of Osteoarthritis Knee: A study in tribal dominant community.

Journal of Ayurveda and integrative medicine·2025
Same author

Understanding the genetic basis of resistance to maydis leaf blight and maturity-related traits in corn.

Frontiers in plant science·2025
Same author

Herbicide and irrigation management options in conventionally-tilled wheat: deciphering water and energy budgeting, and grain and monetary output in north-Indian plains.

Scientific reports·2025

Osteoarticular tuberculosis primarily affects children, with the spine being the most common site. A three-drug regimen combined with physical therapy yielded significant clinical and radiological improvements in most patients.

Area of Science:

  • Orthopedics
  • Infectious Diseases
  • Pediatrics

Background:

  • Osteoarticular tuberculosis is a significant global health concern, particularly in pediatric populations.
  • Early diagnosis and treatment are crucial to prevent long-term complications and deformities.

Purpose of the Study:

  • To analyze the clinical presentation, treatment outcomes, and long-term sequelae of osteoarticular tuberculosis in children.
  • To evaluate the efficacy of a standard three-drug regimen and physical therapy in managing this condition.

Main Methods:

  • Retrospective study of 104 pediatric cases of osteoarticular tuberculosis.
  • Treatment involved a three-drug regimen (rifampicin, isoniazid, ethambutol) with adjusted durations.
  • Management included chemotherapy, bracing, splinting, traction, and physical therapy.

Related Experiment Videos

Main Results:

  • The spine was the most frequently affected site (43%), followed by the hip (14.9%) and knee (10.3%).
  • 75% of patients showed clinical and radiological improvement within one year of treatment.
  • Despite treatment, progressive deformities occurred in a subset of children, including limb shortening and kyphosis.

Conclusions:

  • A multi-drug chemotherapy approach combined with physical therapy is effective in treating pediatric osteoarticular tuberculosis.
  • Long-term monitoring is essential to manage progressive deformities in growing children.
  • Further research into optimizing treatment durations and addressing specific deformities is warranted.