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Heterotopic gastric mucosa in a duplicate gallbladder
Alan G Bailie1, Judy I Wyatt, Maria B Sheridan
1Children's Liver & GI Unit, Leeds Teaching Hospitals NHS Trust, Leeds England, UK.
Journal of Pediatric Surgery
|October 3, 2003
Summary
A rare case of duplicate gallbladder in a child with recurrent pancreatitis revealed heterotopic gastric mucosa. This finding, previously undescribed, may contribute to biliary tract abnormalities and pancreatitis.
Area of Science:
- Gastroenterology and Hepatology
- Pediatric Surgery
- Anatomic Pathology
Background:
- Recurrent acute pancreatitis in children necessitates thorough investigation for underlying causes.
- Biliary tract abnormalities can present with diverse and complex clinical manifestations.
Observation:
- A 7-year-old girl with recurrent acute pancreatitis underwent investigations revealing a biliary tract abnormality.
- Surgical exploration identified a duplicate gallbladder within a single serosal envelope, each with a separate cystic duct.
Findings:
- Histologic examination of the duplicate gallbladder revealed heterotopic fundic-type gastric mucosa in the inferior gallbladder.
- The patient experienced further mild, self-limiting pancreatitis episodes despite surgical correction and absence of residual ectopic mucosa.
Implications:
- This case highlights a novel association between duplicate gallbladder, heterotopic gastric mucosa, and pediatric pancreatitis.
- The findings suggest a potential role for congenital biliary anomalies and ectopic mucosa in the pathogenesis of recurrent pancreatitis.
- Further research is warranted to understand the clinical significance and management of such rare congenital biliary malformations.