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Updated: Aug 17, 2026

A Functional Whole Blood Assay to Measure Viability of Mycobacteria, using Reporter-Gene Tagged BCG or M.Tb (BCG lux/M.Tb lux)
Published on: September 14, 2011
[Comparative analysis of a new modification of segmental tuberculin test with the routine Koch test]
Abstract:
A focal reaction plays the leading role in the assessment of segmental tests (ST). The sensitivity of ST is 72.4% and that of the Koch test is 64.5%, their specificity is 94.1 and 80.0%, respectively. A 10% or more increase in adenosine deaminase during peritoneal fluid ST indicates to the exacerbation of genital tuberculosis. Analysis of the cellular composition of peritoneal fluid from the Douglas space is proposed as a criterion for a focal reaction. There are ultrasound symptoms which accompany the exacerbation of an inflammatory process in the genitals in response to ST and which are indicative of a positive focal reaction. The minimum tuberculin load and lack of contraindications allow ST to be introduced into the practical work of tuberculosis facilities.
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