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Related Experiment Videos

Biventricular support with the Jarvik 2000 axial flow pump: a feasibility study.

Branislav Radovancevic1, Igor D Gregoric, Daniel Tamez

  • 1Cardiopulmonary Transplantation Service and Cullen Cardiovascular Research Laboratories, Texas Heart Institute at St. Luke's Episcopal Hospital, PO Box 20345, Houston, TX 77225-0345, USA.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|October 4, 2003
PubMed
Summary

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The Jarvik 2000 axial flow pump is a feasible option for right ventricular assist device (RVAD) support in patients with heart failure. This device can provide effective biventricular support, aiding circulation when the left ventricular assist device (LVAD) is insufficient.

Area of Science:

  • Cardiovascular Surgery
  • Medical Devices
  • Hemodynamics

Background:

  • Patients with congestive heart failure requiring left ventricular assist device (LVAD) support may develop right ventricular dysfunction.
  • Right ventricular assist devices (RVADs) are sometimes necessary to manage this complication.

Purpose of the Study:

  • To assess the feasibility of using the clinically available Jarvik 2000 axial flow ventricular assist device as an RVAD.
  • To evaluate the hemodynamic effects of biventricular support using Jarvik 2000 pumps in a calf model.

Main Methods:

  • Two Corriente crossbred calves underwent implantation of Jarvik 2000 pumps in the left ventricle and right atrium via left thoracotomy.
  • Hemodynamic parameters were analyzed at various LVAD and RVAD speeds in a mechanically fibrillated heart.

Related Experiment Videos

  • Right atrial implantation required no device or surgical technique modification.

    • Main Results:

    • Satisfactory biventricular support was achieved during fibrillation.
    • Mean aortic pressure increased from 34 mm Hg (pumps off) to 78 mm Hg (pumps at 4.8 L/min flow rate).
    • The Jarvik 2000 demonstrated capability for complete circulatory support.

    Conclusions:

    • The Jarvik 2000 pump is a feasible option for RVAD implantation after LVAD placement.
    • This device can provide chronic circulatory support and is powered by external batteries.
    • It is capable of supporting circulation in patients with global heart failure.