Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Experience with bone marrow trephine biopsy.

J D Rege1, A M Phatak, R Issac

  • 1Topiwala National Medical College, Bombay.

The Journal of the Association of Physicians of India
|April 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Current concepts in the management of ankle arthritis.

Journal of clinical orthopaedics and trauma·2020
Same author

SU-E-T-472: Characterization of the Very High Energy Electrons, ISO - 250 MeV (VHEE) Beam Generated by ALPHA-X Laser Wakefield Accelerator Beam Line for Utilization in Monte Carlo Simulation for Biomedical Experiment Planning.

Medical physics·2017
Same author

Electro-optic measurement of terahertz pulse energy distribution.

The Review of scientific instruments·2009
Same author

Utilization of antihepatocyte clone OCH1E5 (Hep Par 1) in histological evaluation of liver tumors.

Indian journal of pathology & microbiology·2006
Same author

Disseminated histoplasmosis mimicking laryngeal carcinoma from central India--a case report.

Indian journal of pathology & microbiology·2006
Same author

Radiation sources based on laser-plasma interactions.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2006

Bone marrow trephine biopsies are valuable for diagnosing cytopenias when aspiration fails. These biopsies also aid in staging lymphomas and multiple myeloma.

Area of Science:

  • Hematology
  • Pathology
  • Oncology

Background:

  • Bone marrow examination is crucial for diagnosing various hematologic conditions.
  • Bone marrow aspiration can be limited by hypocellularity or dry tap, necessitating alternative methods.

Purpose of the Study:

  • To evaluate the utility of bone marrow trephine biopsies in clinical practice.
  • To assess the role of trephine biopsies in the differential diagnosis of cytopenias and staging of hematologic malignancies.

Main Methods:

  • Retrospective analysis of 110 bone marrow trephine biopsies.
  • Specimens were collected between January 1987 and July 1989.
  • Zenker's acetic acid fixative and routine paraffin embedding were employed.

Main Results:

Related Experiment Videos

  • Trephine biopsies proved useful in the differential diagnosis of cytopenias.
  • Effectiveness was noted particularly in cases with hypocellular bone marrow aspirates or dry taps.
  • The procedure was also beneficial for staging lymphomas and multiple myeloma.

Conclusions:

  • Bone marrow trephine biopsy is an effective diagnostic tool, especially when bone marrow aspiration is non-diagnostic.
  • This method provides critical information for the diagnosis and staging of hematologic disorders.