Related Experiment Video

Updated: Aug 19, 2026

Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae
09:12

Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae

Published on: January 17, 2014

Characterization and distribution of Pasteurella species recovered from infected humans

E Holst1, J Rollof, L Larsson

  • 1Department of Medical Microbiology, Lund University, Sölvegatan, Sweden.

Journal of Clinical Microbiology
|November 1, 1992
PubMed

Insights

This study identified Pasteurella strains from human infections, finding Pasteurella multocida subspecies were most common in severe cases. Cellular fatty acid and enzyme profiles did not differentiate species, though animal bite association varied.

Area of Science:

  • Medical Microbiology
  • Bacteriology
  • Infectious Diseases

Background:

  • Pasteurella species are known zoonotic bacteria, frequently associated with animal bites.
  • Accurate identification and characterization of Pasteurella strains are crucial for understanding human infections.

Purpose of the Study:

  • To biochemically characterize Pasteurella strains isolated from human infections.
  • To investigate the relationship between different Pasteurella species and their clinical relevance.
  • To analyze cellular fatty acid composition and enzymatic activities for species differentiation.

Main Methods:

  • Biochemical characterization of 159 Pasteurella strains from human infections.
  • Analysis of cellular fatty acid profiles using gas chromatography.
  • Assessment of enzymatic activities for each identified species.
  • Toxin production screening in a subset of strains.

Main Results:

  • Identified 159 strains belonging to Pasteurella multocida (subsp. multocida and septica), Pasteurella canis, Pasteurella stomatis, and Pasteurella dagmatis.
  • Cellular fatty acid composition and enzymatic activities were indistinguishable across different Pasteurella species.
  • Toxin production was rare, observed only in one strain each of P. multocida subsp. multocida and P. canis.
  • P. multocida subspecies were associated with more severe infections, while P. canis was linked to dog bites.

Conclusions:

  • Biochemical markers like fatty acids and enzymes are insufficient for differentiating Pasteurella species.
  • Pasteurella multocida subspecies are significant pathogens in human infections, often linked to cat bites/scratches.
  • P. canis is specifically associated with dog bite-related infections.

More Related Videos

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae06:04

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

Published on: February 24, 2023

Polymerase Chain Reaction and Dot-Blot Hybridization for Leptospira Detection in Water Samples06:05

Polymerase Chain Reaction and Dot-Blot Hybridization for Leptospira Detection in Water Samples

Published on: June 14, 2024

Related Concept Videos

Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...
Inhalation Anthrax01:25

Inhalation Anthrax

Anthrax is a zoonotic disease caused by Bacillus anthracis, a Gram-positive, spore-forming bacterium. It primarily affects herbivorous animals but can be transmitted to humans through skin contact, ingestion, or inhalation of spores.Cutaneous anthrax, the most common form, typically results from direct contact with bacterial spores through skin abrasions and is generally less severe. Gastrointestinal anthrax results from eating undercooked or contaminated meat. It affects the mouth, throat, or...
Plague01:24

Plague

Plague is a highly virulent zoonotic disease caused by Yersinia pestis, a Gram-negative, facultatively anaerobic coccobacillus. This pathogen primarily circulates among rodent populations and is transmitted to humans through the bite of infected fleas. Additional transmission routes include direct contact with infected animal tissue or inhalation of respiratory droplets from individuals with pneumonic plague. These multiple transmission pathways highlight the bacterium’s potential for rapid...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...