Related Experiment Videos
Buttock soft tissue sarcoma: clinical features, treatment, and prognosis
K A Behranwala1, P Barry, R A'Hern
1Sarcoma and Melanoma Unit, Royal Marsden National Health Service Trust, South Kensington, London, United Kingdom. kbelranwala@hotmail.com
Annals of Surgical Oncology
|October 7, 2003
Summary
This study characterizes buttock sarcomas in adults, finding tumor size and grade are key predictors of survival. Understanding these factors is crucial for managing this rare but serious condition.
Area of Science:
- Oncology
- Surgical Oncology
- Orthopedic Oncology
Background:
- Primary buttock soft tissue sarcomas are infrequently reported in adults.
- This study aims to characterize buttock sarcomas and define their natural history.
Purpose of the Study:
- To present the experience of buttock sarcomas at a major cancer center.
- To better define the natural history and outcomes of buttock sarcomas.
Main Methods:
- Retrospective review of adult buttock tumors (1990-2002) from a prospective sarcoma database.
- Analysis of 73 cases, including histological type, tumor grade, location, and treatment.
- Evaluation of local recurrence, distant metastasis, and survival rates.
Main Results:
- Liposarcoma, leiomyosarcoma, and synovial sarcoma were the most frequent types.
- Most tumors were deep to the fascia, with varying grades and sizes.
- Local recurrence and distant metastasis rates were 20.9% and 35 patients, respectively; 2-year survival was 64.1%.
Conclusions:
- Buttock sarcomas pose surgical challenges due to anatomical location and potential pelvic extension.
- Tumor size and grade are independent predictors of disease-free and overall survival.
- Further research is needed to optimize management strategies for buttock sarcomas.