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Updated: Aug 5, 2026

13:19
Mouse Model for Pancreas Transplantation Using a Modified Cuff Technique
Published on: December 16, 2017
[Temporary normalization of blood sugar, in a totally pancreatectomized dog, after placing an artificial insulin
Abstract:
Islets of Langerhans were stablished in the spaces between 9 synthetic hollowfibers in a "bio-artificial insulin distributor" which was implanted in the carotid artery of totally pancreatectomized dogs. Normo-glycemia was restored after 4 hours. The major problem encountered was coagulation in the fibers. Presently, this limits the prolonged utilization of this system.

