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Updated: Aug 30, 2026
Peptide-based Identification of Functional Motifs and their Binding Partners
Published on: June 30, 2013
Synthetic peptides in the diagnosis of HIV infection
Maria Claudia Alcaro1, Elisa Peroni, Paolo Rovero
1Laboratory of Peptide Chemistry & Immunology, Dipartimento di Chimica Organica "Ugo Schiff", Università di Firenze, Polo Scientifico, I-50019 Sesto Fiorentino (FI), Italy.
Peptide-based enzyme-linked immunosorbent assays have been found to be enough sensitive and specific for the diagnosis of human immunodeficiency virus specific antibodies in acquired immunodeficiency syndrome patients. This review provides an overview of the most important peptides developed for use as synthetic antigens in immunodiagnosis of HIV-infected patients. In particular, many studies have been devoted to discriminate between the two retroviruses HIV-1 and HIV-2, as well as different subtypes.
Peptide-based enzyme-linked immunosorbent assays have been found to be enough sensitive and specific for the diagnosis of human immunodeficiency virus specific antibodies in acquired immunodeficiency syndrome patients. This review provides an overview of the most important peptides developed for use as synthetic antigens in immunodiagnosis of HIV-infected patients. In particular, many studies have been devoted to discriminate between the two retroviruses HIV-1 and HIV-2, as well as different subtypes.
