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Updated: Jul 25, 2026
A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Direct laparoscopic venous sampling to diagnose a small Sertoli-Leydig tumor
L C White1, K D Buchanan, T D O'Leary
1Department of Obstetrics/Gynecology, Arnold Palmer Hospital, Orlando Regional Healthcare System, Orlando, FL 32806, USA.
Background:
Sertoli-Leydig cell tumors (SLCT) constitute only 0.5% of all primary ovarian neoplasms. We report a unique diagnostic method (selective laparoscopic venous sampling) and a rare case of a contralateral second primary tumor.
Case:
A 14-year-old female presented with hyperandrogenic complaints and an increased serum testosterone. Ovarian origin was confirmed by direct laparoscopic ovarian blood sampling. A right salpingo-oophorectomy was performed. The pathological diagnosis was SLCT of intermediate differentiation. Three years later, the patient presented again with an increased serum testosterone. A solid tumor in the left ovary was excised. The pathology was SLCT of intermediate differentiation. The patient remains disease-free.
Conclusions:
Direct laparoscopic venous sampling is used to diagnose a small SLCT in a teenage patient.
