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Published on: March 28, 2025
Late reoperation for proximal aortic and arch complications after previous composite graft replacement in Marfan
Teruhisa Kazui1, Katsushi Yamashita, Hitoshi Terada
1First Department of Surgery, Hamamatsu University School of Medicine, Handayama, Hamamatsu, Japan. tkazui@hama-med.ac.jp
Background:
Marfan patients who received composite graft replacement for proximal aortic disease frequently require late reoperation. The initial surgical technique for this lesion remains controversial.
Methods:
Fourteen Marfan patients who received composite graft replacement for annuloaortic ectasia with or without aortic dissection required late reoperation thorough re-median sternotomy. The techniques used for an initial composite graft replacement were the original Bentall procedure in 11 patients, the Cabrol procedure in 2, and coronary button technique in 1. Reoperation was indicated for prosthesis-related complications in 10 patients, distal aortic lesion in 13, or for both lesions in 8. Reoperations were performed, on average, 8.4 years after an initial operation. Reoperative procedures included re-composite graft replacement in 1 patient, total arch replacement in 5, and re-composite graft replacement with total arch replacement in 8.
Results:
There were two in-hospital deaths (14.3%). Although pseudoaneurysms of the coronary artery or distal aorta occurred in the original Bentall or Cabrol procedures, true aneurysms of the coronary artery were noted even in the coronary button technique. Six patients required a total of eight subsequent descending or thoracoabdominal aortic replacements for an aneurysmal formation of a distal false lumen.
Conclusions:
The coronary button technique, with a small side hole for coronary anastomosis, is the procedure of choice for annuloaortic ectasia because it reduces the risk of coronary artery-related complications. Concomitant total arch replacement may be recommended for annuloaortic ectasia with DeBakey type I aortic dissection in selected patients to avoid the risk of reoperation on the aortic arch.
Insights
For Marfan syndrome patients undergoing aortic graft replacement, the coronary button technique is preferred to minimize coronary complications. Early total arch replacement may prevent future aortic arch reoperations.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Medical Engineering
Background:
- Marfan syndrome patients often require reoperation after composite graft replacement for proximal aortic disease.
- The optimal initial surgical technique for proximal aortic disease in Marfan syndrome remains debated.
Purpose of the Study:
- To evaluate reoperation outcomes in Marfan patients with composite graft replacement for annuloaortic ectasia.
- To compare the effectiveness of different initial surgical techniques, including Bentall, Cabrol, and coronary button procedures.
- To identify risk factors and recommend strategies for preventing late aortic complications.
Main Methods:
- Retrospective analysis of 14 Marfan patients undergoing reoperation for composite graft complications.
- Review of initial procedures: Bentall (11), Cabrol (2), coronary button (1).
- Analysis of indications for reoperation (prosthesis-related, distal aorta) and reoperative procedures performed.
Main Results:
- In-hospital mortality was 14.3% (2 deaths).
- Coronary artery pseudoaneurysms occurred with Bentall and Cabrol procedures; true aneurysms were seen even with the coronary button technique.
- Six patients required subsequent aortic replacements for distal aneurysmal formation.
Conclusions:
- The coronary button technique is recommended for annuloaortic ectasia due to reduced coronary artery complications.
- Concomitant total arch replacement may be beneficial for selected Marfan patients with DeBakey type I aortic dissection to prevent arch reoperation.
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