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[Relevance of reactive fillets in detecting urinary infections in African paediatric environment]
Diarra Yé1, Adjouma Combary, Ramata Ouédraogo-Traoré
1Service de pédiatrie, CHN YO de Ouagadougou, 01 BP 5488, Ouagadougou 01, Burkina Faso. yediarra@hotmail.com
Insights
Pediatricians in Africa can use reactive strips to help diagnose urinary tract infections in infants. A negative test result can rule out infection, while a positive result indicates a strong possibility of infection.
Area of Science:
- Pediatric Infectious Diseases
- Clinical Diagnostics
- Urology
Context:
- African pediatricians face numerous challenges managing common childhood illnesses.
- Urinary tract infections (UTIs) in infants often present with non-specific symptoms.
- Systematic screening for UTIs in infants is crucial despite other prevalent pathologies.
Purpose:
- To evaluate the diagnostic accuracy of reactive strips for detecting urinary tract infections in African infants.
- To determine the optimal use of reactive strips (Multistix 8 SG) in a resource-limited setting.
Summary:
- Reactive strips, specifically Multistix 8 SG, show promising diagnostic values for UTIs in infants.
- Leukocyte detection demonstrated high sensitivity (95%).
- Combining leukocyte and nitrite tests yielded the best specificity (77.1%), positive predictive value (68.1%), and negative predictive value (86%).
Impact:
- Reactive strips can be a valuable, accessible tool for clinicians in daily pediatric practice in Africa.
- Negative test results can effectively exclude UTIs, guiding clinical management.
- Positive test results warrant careful consideration and rigorous follow-up for suspected UTIs.
Abstract:
It is quite obvious that African paediatricians are facing numerous challenges. However, their daily fight against frequent pathologies such as malaria, diarrhoeal diseases and respiratory infections should not prevent them from taking into consideration the existence of other pathologies, particularly urinary infections. The clinical picture of urinary infections which is often polymorphic would require a systematic test among infants. Reactive fillets may therefore be relevant in detecting such urinary infections. This survey shows that the best intrinsic values of the fillets used (multistix 8 SG) are reached with leucocytes (sensibility: 95%) and with the combination of leucocytes and nitrites (specificity: 77.1%). The best predictable validities were obtained with the combination of leucocytes and nitrites (positive predictable value: 68.1%) as well as with the combination of leucocytes or nitrites (negative predictable value: 86%). In the daily practice, reactive fillets may turn out to be helpful to the clinician. The negativity of both tests speaks for the isolation and exclusion of urinary infections. On the other hand, the positivity of both tests highlights a strong urinary infection which is subject to a careful and rigorous use of fillets.
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